High-throughput RNA sequencing of the T cell receptor alpha and beta chains for simultaneous clonality and biological analyses in Sezary syndrome.

Gonzalo Blanco Daniel López-Aventín Ramon Maria Pujol Andrea Gómez-Llonín Anna Puiggros Manuela López-Sánchez Teresa Estrach Mª Pilar García-Muret Ingrid López-Lerma Octavio Servitje Beatriz Bellosillo Manuel Muro Blanca Espinet Raquel Rabionet Janssen Fernando Gallardo

Published in: Journal of clinical laboratory analysis (2023)

Besides detecting clonality, these findings shed light on the nature of SS-related antigens, pointing to RNA sequencing as a useful tool for simultaneous clonality and biological analysis in SS.

Keyphrases

single cell
high throughput
dendritic cells
case report
immune response
binding protein
data analysis