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Antitumor activity and efficacy of shorter versus longer duration of anthracycline-taxane neoadjuvant chemotherapy in stage II-III HER2-negative breast cancer: a 10-year, retrospective analysis.

Riccardo LobefaroEmma ZattarinFederico NichettiMichele PrisciandaroFrancesca LigorioMarta BrambillaPierangela SepeFrancesca CortiGiorgia PeverelliArianna OttiniTeresa BeninatoLaura MazzeoCarmen G ReaGabriella MarianiFilippo de BraudGiulia V BianchiClaudio VernieriGiuseppe Capri
Published in: Therapeutic advances in medical oncology (2020)
Shorter duration of neoadjuvant anthracycline-taxane ChT was not associated with worse clinical outcomes in patients with stage II-III BC. Prospective studies are needed to evaluate whether the duration of neoadjuvant anthracycline-taxane-based ChT can be reduced in specific patient subgroups without negatively affecting clinical outcomes.
Keyphrases
  • neoadjuvant chemotherapy
  • locally advanced
  • lymph node
  • rectal cancer
  • metastatic breast cancer
  • squamous cell carcinoma
  • sentinel lymph node
  • radiation therapy
  • case report
  • young adults