Treatment Outcomes in Patients with Advanced Fibrolamellar Hepatocellular Carcinoma Under Systemic Treatment: Analysis of Clinical Characteristics, Management, and Radiomics.
Leonardo Gomes da FonsecaVictor Junji YamamotoMateus Trinconi CunhaGiovanna Sawaya TorreRaphael Leonardo Cunha de AraujoGilton Marques FonsecaAndre Tsin Chih ChenAline Lopes ChagasPaulo HermanVenancio Avancini Ferreira AlvesFlair Jose CarrilhoPublished in: Journal of hepatocellular carcinoma (2023)
FLHCC has unique features compared to conventional HCC, including young onset, gender balance, and absence of hepatopathy. Systemic therapies can provide encouraging survival, but lack of uniformity precludes defining a preferable regimen. Radiomics and NLR were suggested to correlate with prognosis and warrant further validation.