Identifying Therapies to Combat Epithelial Mesenchymal Plasticity-Associated Chemoresistance to Conventional Breast Cancer Therapies Using An shRNA Library Screen.
Sugandha BhatiaTony BlickCletus PintoMark WalthamJames H MonkmanEkaterina IvanovaPamela M PollockShivashankar H NagarajAdrian P WiegmansIzhak HavivKaylene J SimpsonErik W ThompsonPublished in: Cancers (2020)
Taken together, a cell polarity/EMP-enriched shRNA library screen identified relevant gene products that could be targeted alongside current chemotherapeutic agents for the treatment of invasive BC.