Natural Transmission of Bat-like Severe Acute Respiratory Syndrome Coronavirus 2 Without Proline-Arginine-Arginine-Alanine Variants in Coronavirus Disease 2019 Patients.

Yik Chun WongSiu Ying LauKelvin Kai Wang ToBobo Wing Yee MokXin LiPui WangShaofeng DengKin Fai WooZhenglong DuCun LiJie ZhouJasper Fuk Woo ChanKwok Yung YuenHong-Lin Chen Zhiwei Chen

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)

Our findings demonstrate that bat-like SARS-CoV-2ΔPRRA not only naturally exists but remains transmissible in COVID-19 patients, which has significant implications regarding the zoonotic origin and natural evolution of SARS-CoV-2.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
end stage renal disease
nitric oxide
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
gene expression
copy number
patient reported outcomes
genome wide
patient reported