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Effect of Statins on Platelet Activation and Function: From Molecular Pathways to Clinical Effects.

Antonio NennaFrancesco NappiMario LusiniUmberto Maria SatrianoDavide SchilirĂ²Cristiano SpadaccioMassimo Chello
Published in: BioMed research international (2021)
There are many pathways potentially responsible for the interactions between statins and platelets. Their effect appears to be closely related, and each single effect can be barely measured. Also, the same compound might have complex downstream signaling with potentially opposite effects, i.e., beneficial or deleterious. The multiple clinical implications that can be derived as a result of this interaction, however, represent an excellent reason to develop future in-depth studies.
Keyphrases
  • cardiovascular disease
  • type diabetes
  • current status
  • red blood cell
  • case control