Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control.

Franziska S RathjensAlica BlenkleLavanya M IyerAnke RengerFahima SyedaClaudia NoackAndreas JungmannMatthias DewenterKarl ToischerAli El-ArmoucheOliver J MüllerLarissa FabritzWolfram-Hubertus ZimmermannLaura C ZelarayanMaria-Patapia Zafeiriou

Published in: Cardiovascular research (2022)

This study uncovers a novel cardioprotective role of TBX5 in the adult heart and provides preclinical evidence for the therapeutic value of TBX5 protein normalization in the control of arrhythmia.

Keyphrases

cell therapy
heart failure
atrial fibrillation
stem cells
protein protein
small molecule
mesenchymal stem cells