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Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control.

Franziska S RathjensAlica BlenkleLavanya M IyerAnke RengerFahima SyedaClaudia NoackAndreas JungmannMatthias DewenterKarl ToischerAli El-ArmoucheOliver J MüllerLarissa FabritzWolfram-Hubertus ZimmermannLaura C ZelarayanMaria-Patapia Zafeiriou
Published in: Cardiovascular research (2022)
This study uncovers a novel cardioprotective role of TBX5 in the adult heart and provides preclinical evidence for the therapeutic value of TBX5 protein normalization in the control of arrhythmia.
Keyphrases
  • cell therapy
  • heart failure
  • atrial fibrillation
  • stem cells
  • protein protein
  • small molecule
  • mesenchymal stem cells