Serum Concentration of Vancomycin Is a Diagnostic Predictor of Nephrotoxic Acute Kidney Injury in Septic Patients in Clinical and Surgical Wards.
Welder ZamonerIsabella Gonçalves PierriKarina Zanchetta Cardoso EidLais Maria Bellaver de AlmeidaAdriano Dos SantosAndré Luís BalbiDaniela PoncePublished in: Infection and drug resistance (2020)
Serum concentration of vancomycin is an excellent predictor of AKI in patients admitted to wards, preceding the diagnosis of AKI by at least 72 hours. Toxic concentrations of vancomycin are associated with AKI, and AKI was a risk factor for death. Also, serum concentration of vancomycin >21.5 mg/L was the only variable associated with death in the Cox model.