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MiR-339-5p Inhibits Ferroptosis by Promoting Autophagic Degradation of FTH1 Through Targeting ATG7 in Liver Cancer Cells.

Fei CaoWeiyuan HaoWeiren LiangHui ZengJiaping Zheng
Published in: Clinical Medicine Insights. Oncology (2024)
We provide important evidence that the miR-339 inhibition activates of the autophagy pathway to promote ferroptosis by degrading FTH1 in liver cancer cells. We found that miR-339 regulates the balance between ferroptosis and autophagy in liver cancer cells.
Keyphrases
  • cell death
  • cell proliferation
  • long non coding rna
  • long noncoding rna
  • endoplasmic reticulum stress
  • signaling pathway
  • oxidative stress