Radical prostatectomy cancer grade and percentage of Gleason pattern 4 estimated by global vs individual tumor grading correlate differently with the risk of biochemical recurrence in Grade Group 2 and 3 cancers.
Oleksandr N KryvenkoJonathan I EpsteinAli MerheOleksii A IakymenkoRicardo De Almeida E Silva JuniorDimple Kumar ChanamoluLaurence M BriskiDeukwoo KwonIvan NemovSanoj PunnenAlan PollackRadka StoyanovaDipen J ParekhMerce JordaMark L GonzalgoPublished in: American journal of clinical pathology (2024)
Grade Group, GP4%, and margin status derived by global vs individual tumor grading predict postoperative biochemical recurrence statistically significantly differently. This difference has important implications if results derived from cohorts graded using different methods are compared.