Hemophilia prophylaxis adherence and bleeding using a tailored, frequency-escalated approach: The Canadian Hemophilia Primary Prophylaxis Study.
Saunya DoverVictor S BlanchetteDarius WrathallEleanor PullenayegumDaniel KazandjianByron SongSue Ann HawesStéphanie CloutierGeroges E RivardRobert J KlaassenElizabeth ParadisNicole LaferriereAnn Marie StainAnthony K C ChanSara J IsraelsRoona SinhaMacGregor SteeleJohn K M WuBrian M FeldmanPublished in: Research and practice in thrombosis and haemostasis (2020)
This cohort had high rates of adherence to the prescribed prophylaxis regimen. Initiating prophylaxis with once-weekly infusions facilitated adherence to the prophylaxis regimen in this cohort of boys with severe hemophilia A started on primary prophylaxis at a very young age.