Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age: A Longitudinal Cohort Study.
Sivaniya SubramaniapillaiLouise S SchindlerPaul RedmondMark E BastinJoanna Marguerite WardlawMaria Del Carmen Valdés-HernándezSusana Muñoz ManiegaBenjamin AribisalaLars Tjelta WestlyeWilliam CoathJames GrovesDavid M CashJosephine BarnesSarah-Naomi JamesCarole Helene SudreFrederik BarkhofMarcus RichardsJanie CorleyTom C RussSimon R CoxJonathan M SchottJames H ColeAnn-Marie G de LangePublished in: Neurology (2024)
status, and brain age. Our findings highlight the necessity of sex-stratified analyses to elucidate the role of CMRs in individual aging trajectories, providing a basis for developing personalized preventive interventions.