Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.

Li ZhangJingtian LiangHao QinYin LvXiucheng LiuZhuoqun LiZhixiang ChaoCaili JiaXichun QinHao Zhang

Published in: Journal of experimental & clinical cancer research : CR (2023)

Our study reveals a novel lncRNA AC016727.1/BACH1/HIF-1α signaling loop in the progression of NSCLC under hypoxic conditions, suggesting that lncRNA AC016727.1 could act as a useful biomarker for NSCLC and a new therapeutic target.

Keyphrases

small cell lung cancer
advanced non small cell lung cancer
long non coding rna
transcription factor
endothelial cells
long noncoding rna
brain metastases
tyrosine kinase