Outcome of extracorporeal photopheresis in mycosis fungoides patients is not predicted by quotients of systemic immune-inflammatory biomarkers.

Thilo GambichlerJan SpäthShayda SaidChristina H ScheelLaura SusokRene Stranzenbach

Published in: Journal of clinical apheresis (2022)

ECP appears to be beneficial in early-stage CTCL as well. Lower percentages of circulating CD4+/CD7- and CD4+/CD26- lymphocytes at baseline correlate with response to ECP. In this study, however, baseline SIIBs did not appear to serve as suitable biomarkers for the prediction of treatment outcome and LS survival.

Keyphrases

early stage
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
oxidative stress
squamous cell carcinoma
peripheral blood
radiation therapy
drug induced
sentinel lymph node