Altered circulatory levels of miR-128, BDNF, cortisol and shortened telomeres in patients with type 2 diabetes and depression.

Paramasivam PrabuSubramani PoongothaiCoimbatore Subramanian ShanthiraniRanjit Mohan AnjanaViswanathan MohanMuthuswamy Balasubramanyam

Published in: Acta diabetologica (2020)

Patients with type 2 diabetes and depression exhibited increased circulatory levels of miR-128 and serum cortisol and decreased levels of BDNF and shortened telomeres. These neuroendocrine signatures were more markedly altered in those with combined diabetes and depression.

Keyphrases

depressive symptoms
cell proliferation
long non coding rna
sleep quality
type diabetes
long noncoding rna
cardiovascular disease
extracorporeal membrane oxygenation
gene expression
physical activity
skeletal muscle
dna methylation
insulin resistance