Polymorphic variants of alkaline phosphatase gene correlate with clinical signs of adult hypophosphatasia?

L MasiF MariniF FranceschelliG LeonciniL CianferottiF CioppiF GiustiG MarcucciG GronchiMaria Luisa Brandi

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2021)

The genetic analysis and presence of some polymorphic variants may be an instrument to confirm clinical and biochemical data, consider adult HPP, and help clinicians be cautious in the administration of anti-reabsorption drugs.

Keyphrases

copy number
palliative care
gene expression
big data
young adults
dna methylation
smoking cessation