Different antibiotic protocols in the treatment of severe chronic periodontitis: A 1-year randomized trial.
Ivan BorgesMarcelo FaveriLuciene Cristina FigueiredoPoliana Mendes DuarteBelén Retamal-ValdesSheyla Christinne Lira MontenegroMagda Gomes FeresPublished in: Journal of clinical periodontology (2017)
The adjunctive use of 400 or 250 mg of MTZ plus 500 mg of AMX/TID/14 days offers statistically significant and clinically relevant benefits over those achieved with SRP alone in the treatment of severe GChP. The added benefits of the 7-days regimen in this population were less evident. (ClinicalTrials.gov NCT02735395).