Neuropsychiatric events in systemic lupus erythematosus: a longitudinal analysis of outcomes in an international inception cohort using a multistate model approach.
John G HanlyMurray B UrowitzCaroline GordonSang-Cheol BaeJuanita Romero-DiazJorge Sanchez-GuerreroSasha BernatskyAnn E ClarkeDaniel J WallaceDavid Alan IsenbergAnisur RahmanJoan T MerrillPaul R FortinDafna D GladmanIan N BruceMichelle A PetriEllen M GinzlerMary Anne DooleyRosalind Ramsey-GoldmanSusan ManziAndreas JönsenGraciela S AlarcónRonald F van VollenhovenCynthia AranowMeggan MackayGuillermo Ruiz-IrastorzaSam LimMurat InancKenneth C KalunianSøren JacobsenChristine A PeschkenDiane L KamenAnca AskanaseVernon FarewellPublished in: Annals of the rheumatic diseases (2020)
NP events occur most frequently around the diagnosis of SLE. Although the majority of events resolve they are associated with reduced HRQoL and excess mortality. Multistate modelling is well suited for the assessment of NP events in SLE.