Association Between Serum 25-Hydroxyvitamin D Concentrations, CDX2 Polymorphism in Promoter Region of Vitamin D Receptor Gene, and Chronic Pain in Rural Japanese Residents.

Keita SuzukiHiromasa TsujiguchiAkinori HaraOanh Kim PhamSakae MiyagiThao Thi Thu NguyenHaruki NakamuraFumihiko Suzuki Tomoko KasaharaYukari ShimizuYohei YamadaYasuhiro KambayashiHirohito TsuboiTakehiro Sato Takayuki KannonKazuyoshi HosomichiAtsushi Tajima Toshinari TakamuraHiroyuki Nakamura

Published in: Journal of pain research (2022)

These results suggest that sufficient serum 25(OH)D concentration reduces the risk of CP in individuals with the minor allele of the CDX2 polymorphism.

Keyphrases

chronic pain
dna methylation
gene expression
south africa
transcription factor
genome wide analysis