Aneuploidy Landscape in Precursors of Ovarian Cancer.
Yeh WangChristopher B DouvilleYen-Wei ChienBrant G WangChi-Long ChenAndre PintoSaron Ann SmithRonny DrapkinMichael Herman ChuiTricia NumanRussell VangNickolas PapadopoulosTian-Li WangIe-Ming ShihPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Morphologically similar STICs are molecularly distinct. The REAL-FAST assay identifies a potentially "aggressive" STIC subgroup harboring unique DNA aneuploidy that is associated with increased cellular proliferation and discohesive growth. REAL-FAST offers a highly reproducible adjunct technique to assist the diagnosis of STICs.