Aneuploidy Landscape in Precursors of Ovarian Cancer.

Yeh Wang Christopher Douville Yen-Wei Chien Brant G Wang Chi-Long Chen Andre Pinto Saron Ann Smith Ronny Drapkin Michael Herman Chui Tricia Numan Russell Vang Nickolas Papadopoulos Tian-Li Wang Ie-Ming Shih

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)

Morphologically similar STICs are molecularly distinct. The REAL-FAST assay identifies a potentially "aggressive" STIC subgroup harboring unique DNA aneuploidy that is associated with increased cellular proliferation and discohesive growth. REAL-FAST offers a highly reproducible adjunct technique to assist the diagnosis of STICs.

Keyphrases

circulating tumor
high throughput
genome wide
single molecule
cell free
single cell
gene expression
circulating tumor cells
double blind