Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer.

Mario Cangiano Magda GrudniewskaMark J SaljiMatti NykterGuido W Jenster Alfonso Urbanucci Zoraide GranchiBart JanssenGraham Hamilton Hing Y LeungInès J Beumer

Published in: Cancers (2021)

We have characterised gene regulatory networks from preclinical prostate orthografts and applied transcriptomic data from three clinical cohorts to evaluate the prognostic potential of the JMJD6 regulon.

Keyphrases

prostate cancer
network analysis
radical prostatectomy
endothelial cells
stem cells
machine learning
cell therapy
rna seq
bone marrow
human health
climate change