A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade.
Hong YanZhong-Yi MaoZhong-Wei HouJin-Shuai SongHai-Chao XuPublished in: Beilstein journal of organic chemistry (2019)
A diastereoselective approach to axially chiral imidazopyridine-containing biaryls has been developed. The reactions proceed through a radical cyclization cascade to construct the biaryls with good to excellent central-to-axial chirality transfer.