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Maximum Acceptable Risk Estimation Based on a Discrete Choice Experiment and a Probabilistic Threshold Technique.

Jorien VeldwijkRachael Lynn DiSantostefanoEllen JanssenGwenda SimonsMatthias EnglbrechtKarin Schölin BywallChristine RadawskiKarim RazaBrett HauberMarie Falahee
Published in: The patient (2023)
Maximum acceptable risk estimate confidence intervals based on a DCE and a PTT overlapped for two out of the three included risk attributes. More respondents rated the DCE as easier to understand. This may suggest that the DCE is better suited in studies estimating maximum acceptable risk for multiple risk attributes of differing severity, while the PTT may be better suited when measuring heterogeneity in maximum acceptable risk estimates or when investigating one or more serious adverse events.
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