The impact of an open or laparoscopic approach on the development of metachronous peritoneal metastases after primary resection of colorectal cancer: results from a population-based cohort study.
Robin J LurvinkAnouk RijkenChecca BakkersValery E LemmensPhilip R de ReuverJurriaan B TuynmanNiels F KokSimon W NienhuijsFelice N van ErningIgnace H J T de HinghPublished in: Surgical endoscopy (2022)
Patients treated with open resection had a significantly higher risk to develop metachronous CPM than patients treated with laparoscopic resection. The mechanisms underlying this phenomenon remain unknown but might be related to differences in per-operative specimen handling, tumour spill, surgical trauma and pro-inflammatory response. This finding might imply the need for a personalized follow-up after primary resection of CRC.