Use of magnetic nanotrap particles in capturing Yersinia pestis virulence factors, nucleic acids and bacteria.
Alexandra N IiShih-Chao LinBenjamin LepeneWeidong ZhouKylene Kehn-HallMonique L van HoekPublished in: Journal of nanobiotechnology (2021)
Upstream use of magnetic CN3080 Nanotrap particles may improve the downstream workflow though binding and enrichment of biomarkers and speed of processing. Utilization of Nanotrap particles can improve detection of Yersinia pestis proteins and nucleic acid from whole human blood and contribute to downstream assays and diagnostics including molecular methods such as sequencing and PCR and protein-based methods.
Keyphrases
- nucleic acid
- molecularly imprinted
- endothelial cells
- escherichia coli
- pseudomonas aeruginosa
- real time pcr
- staphylococcus aureus
- single cell
- binding protein
- high throughput
- antimicrobial resistance
- lymph node metastasis
- induced pluripotent stem cells
- loop mediated isothermal amplification
- protein protein
- single molecule
- cystic fibrosis
- dna binding
- transcription factor
- label free
- solid phase extraction
- quantum dots