VarGoats project: a dataset of 1159 whole-genome sequences to dissect Capra hircus global diversity.
Laure DenoyelleEstelle TalouarnPhilippe BardouLicia ColliAdriana AlbertiCoralie DanchinMarcello Del CorvoStéfan EngelenCéline OrvainIsabelle PalhièreRachel RuppJulien SarryMazdak SalavatiMarcel AmillsEmily L ClarkPaola CrepaldiThomas FarautClet Wandui MasigaFrancois PompanonBenjamin D RosenAlessandra StellaCurtis P Van TassellGwenola Tosser-Kloppnull nullPublished in: Genetics, selection, evolution : GSE (2021)
We report on an unprecedented international effort to characterize the genome-wide diversity of domestic goats. This large range of sequenced individuals represents a unique opportunity to ascertain how the demographic and selection processes associated with post-domestication history have shaped the diversity of this species. Data generated for the project will also be extremely useful to identify deleterious mutations and polymorphisms with causal effects on complex traits, and thus will contribute to new knowledge that could be used in genomic prediction and genome-wide association studies.