Ursolic Acid Inhibits Epithelial-Mesenchymal Transition through the Axl/NF-κB Pathway in Gastric Cancer Cells.

Published in: Evidence-based complementary and alternative medicine : eCAM (2019)

UA can effectively inhibit the proliferation and migration and induce apoptosis of gastric cancer cells. The antitumor effect of UA is conducted by EMT inhibition, which may be associated with the regulation of Axl/NF-κB signaling pathway.

Keyphrases

signaling pathway
epithelial mesenchymal transition
pi k akt
cell cycle arrest
tyrosine kinase
transforming growth factor
induced apoptosis
oxidative stress
endoplasmic reticulum stress
cell death
lps induced
cell proliferation
immune response
toll like receptor