Role of Klotho and N-acetylcysteine in Oxidative Stress Associated with the Vitrification of Ovarian Tissue Cytoprotective Function of Klotho in Cryopreservation.

Boram KimSeon-Mi LeeSang-Jun ParkSanghoon LeeTak Kim

Published in: Tissue engineering and regenerative medicine (2023)

This study highlights Klotho's benefits in inhibiting DNA damage, cell senescence, and apoptosis, including NAC-induced apoptosis, despite its unclear role in vitrification.

Keyphrases

oxidative stress
induced apoptosis
dna damage
endoplasmic reticulum stress
signaling pathway
diabetic rats
ischemia reperfusion injury
dna repair
single cell
transcription factor
endothelial cells
heat shock
stem cells
cell therapy
stress induced
mesenchymal stem cells
cell death