High prevalence of group B streptococcus ST17 hypervirulent clone among non-pregnant patients from a Hungarian venereology clinic.
Szilvia KardosAdrienn TóthpálKrisztina LaubKatalin KristófEszter OstorháziFerenc RozgonyiOrsolya DobayPublished in: BMC infectious diseases (2019)
The presence of silent ermB genes is of worry, as their expression upon macrolide exposure could lead to unforeseen therapeutic failure, while clindamycin is used for intrapartum antibiotic prophylaxis, in case of penicillin allergy. The other alarming result is the high prevalence of ST17 among these strains from STD patients, who could be sources of further infections. This is the first report from Hungary providing both serotyping and genotyping data of GBS isolates. These results could be helpful for vaccine production as the major vaccine candidates are capsular antigens or surface proteins.
Keyphrases
- end stage renal disease
- genome wide
- ejection fraction
- newly diagnosed
- chronic kidney disease
- escherichia coli
- prognostic factors
- peritoneal dialysis
- dendritic cells
- drinking water
- klebsiella pneumoniae
- machine learning
- gene expression
- big data
- immune response
- multidrug resistant
- patient reported outcomes
- transcription factor