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Lack of Interchangeability Between 3 Different Methods for Quantification of Everolimus in Blood: ACMIA, LTIA, and UHPLC-MS/MS.

Chika MiyagiRyota TanakaKen ShiraiwaRyosuke TatsutaHiroki Itoh
Published in: Therapeutic drug monitoring (2024)
Statistically significant proportional biases were observed among the 3 methods. Blood everolimus concentration measurements should be interpreted with caution when switching the quantification methods for therapeutic drug monitoring.
Keyphrases
  • ms ms
  • high resolution mass spectrometry
  • liquid chromatography
  • ultra high performance liquid chromatography