Whole Genome Sequencing Unravels New Genetic Determinants of Early-Onset Familial Osteoporosis and Low BMD in Malta.

Chanelle CiliaDonald FriggieriJosanne VassalloAngela Xuereb-AnastasiMelissa Marie Formosa

Published in: Genes (2022)

Our findings suggest that the identified variants, alone or in combination, could be causal factors of familial osteoporosis and low BMD, requiring replication in larger collections.

Keyphrases

early onset
late onset
postmenopausal women
bone mineral density
copy number
gene expression
body composition
dna methylation