Serum NfL but not GFAP predicts cognitive decline in active progressive multiple sclerosis patients.

Christian BarroBrian C HealyShrishti SaxenaBonnie I GlanzAnu PaulMariann Polgar-TurcsanyiCharles Rg GuttmannRohit BakshiHoward L WeinerTanuja Chitinis

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)

Higher levels of sNfL were associated with cognitive impairment and predicted cognitive decline in MS patients at high risk for having an underlying progressive pathology.

Keyphrases

cognitive decline
multiple sclerosis
end stage renal disease
mild cognitive impairment
ejection fraction
newly diagnosed
chronic kidney disease
cognitive impairment
prognostic factors
patient reported outcomes
white matter
ms ms