Differences in cardiometabolic risk profiles between Chinese and Finnish older adults with glucose impairment and central obesity.

S LeY ZhangA VoutilainenX TanJ LaukkanenC WangSulin Cheng

Published in: Journal of endocrinological investigation (2022)

Our results indicated that Chinese and Finnish older adults of central obesity with prediabetes and T2DM had similar β-cell function. However, Chinese individuals with prediabetes are prone to insulin resistance. Meanwhile, lipid metabolism dysfunction is also different between Chinese and Finnish. Chinese older adults of central obesity with prediabetes showed higher TG, but Finnish showed higher LDL and LDL/HDL. Strategic for T2DM prevention and treatment should be ethnically specific.

Keyphrases

insulin resistance
metabolic syndrome
type diabetes
high fat diet induced
weight loss
physical activity
adipose tissue
weight gain
skeletal muscle
polycystic ovary syndrome
blood pressure
glycemic control
blood glucose
smoking cessation