Login / Signup

Nupr1-mediated vascular smooth muscle cell phenotype transformation involved in methamphetamine induces pulmonary hypertension.

Jie ZhouDan GuoZhen-Zhen XuJia-Shun LiaoXiao-Ting LiKe DuanShi-You ChenWei-Bing Xie
Published in: Cell biology and toxicology (2024)
influx through STIM1-mediated SOCE opening, which promoted METH-induced pulmonary artery remodeling and led to PH formation. These results suggested that Nupr1 played an important role in METH-induced PH and might be a potential target for METH-related PH therapy.
Keyphrases
  • pulmonary artery
  • pulmonary hypertension
  • smooth muscle
  • coronary artery
  • pulmonary arterial hypertension
  • high glucose
  • diabetic rats
  • cell therapy
  • single cell
  • endothelial cells
  • mesenchymal stem cells
  • human health