A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice.
Sacchin ArockiamBrittany StaniforthSacha KepreotisAnnette Marie MaznyczkaHeerajnarain BulluckPublished in: International journal of molecular sciences (2023)
Antiplatelet therapy plays a crucial role in a number of cardiovascular disorders. We currently have a range of antiplatelet agents in our armamentarium. In this review, we aim to summarise the common antiplatelet agents currently available, and their use in clinic practice. We not only highlight recent trials exploring antiplatelet therapy in atherosclerotic cardiovascular disease, but also in trials related to transcatheter aortic valve implantation and coronavirus disease 2019. Inevitably, the antithrombotic benefits of these drugs are accompanied by an increase in bleeding complications. Therefore, an individualised approach to weighing each patient's thrombotic risk versus bleeding risk is imperative, in order to improve clinical outcomes.
Keyphrases
- antiplatelet therapy
- acute coronary syndrome
- percutaneous coronary intervention
- transcatheter aortic valve implantation
- cardiovascular disease
- atrial fibrillation
- coronavirus disease
- clinical practice
- primary care
- aortic valve
- aortic valve replacement
- healthcare
- aortic stenosis
- type diabetes
- heart failure
- transcatheter aortic valve replacement
- quality improvement
- metabolic syndrome