Antagonizing midkine accelerates fracture healing in mice by enhanced bone formation in the fracture callus.

Melanie Haffner-LuntzerAline HeilmannAnna Elise RappRobin RoesslerThorsten SchinkeMichael AmlingAnita IgnatiusAstrid Liedert

Published in: British journal of pharmacology (2016)

We conclude that Mdk-Ab treatment may be a potential novel therapeutic strategy to enhance fracture healing in patients with orthopaedic complications such as delayed healing or non-union formation.

Keyphrases

hip fracture
risk factors
type diabetes
metabolic syndrome
combination therapy
insulin resistance