EGFR and ERBB2 Exon 20 Insertion Mutations in Chinese Non-small Cell Lung Cancer Patients: Pathological and Molecular Characterization, and First-Line Systemic Treatment Evaluation.

Ruiying ZhaoJiaqi LiLianying GuoChan XiangShengnan ChenJikai ZhaoJinchen ShaoLei ZhuMin YeGang QinTianqing ChuYuchen Han

Published in: Targeted oncology (2024)

EGFR/ERBB2-20ins is more common in early lung adenocarcinoma. EGFR-20ins had more variants. In both cohorts, the results for first-line systemic treatments showed no significant difference.

Keyphrases

tyrosine kinase
epidermal growth factor receptor
small cell lung cancer
single cell
cell therapy
copy number
stem cells
gene expression
dna methylation