Hepatic resection after neoadjuvant chemotherapy for patients with liver metastases from colorectal cancer: need for cautious planning.
Young Il KimIn-Ja ParkJeong Eun KimSo Yeon KimJin-Hong ParkJae Hoon LeeTae Yong HaYong Sang HongSun Young KimTae Won KimSeok-Byung LimChang Sik YuJin Cheon KimPublished in: Annals of surgical treatment and research (2019)
Resection margin of the metastatic tumor and ypN status are the only relevant factors for RFS and OS in CLM patients treated with NAC. Despite early and high rates of recurrence, CLM patients treated with NAC who undergo resection and/or local treatment have acceptable OS. Multidisciplinary review of candidates for surgery and cautious planning are crucial for achieving optimal outcomes.