Comparing the Effects of Combined Oral Contraceptives Containing Progestins With Low Androgenic and Antiandrogenic Activities on the Hypothalamic-Pituitary-Gonadal Axis in Patients With Polycystic Ovary Syndrome: Systematic Review and Meta-Analysis.

Mina Amiri Fahimeh Ramezani Tehrani Fatemeh Nahidi Ali Kabir Fereidoun Azizi

Published in: JMIR research protocols (2018)

COCs containing cyproterone acetate can effectively suppress gonadotropins, leading to a decrease in androgenic parameters. Although different products of COCs could significantly suppress the androgenic profile, it seems that products containing cyproterone acetate are more effective in suppressing gonadotropin and estradiol levels in patients with PCOS.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
signaling pathway
type diabetes
patient reported outcomes
metabolic syndrome