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Platelet procoagulant potential is reduced in platelet concentrates ex vivo but appears restored following transfusion.

Ibrahim Tohidi-EsfahaniShereen TanChuen Wen TanLacey JohnsonDenese C MarksVivien M Chen
Published in: Transfusion (2021)
Storage blunts the procoagulant platelet response to agonist stimulation in PCs. Despite this, conventionally stored PCs have high procoagulant potential following transfusion, with a discordant, persistent reduction in P-selectin response.
Keyphrases
  • cardiac surgery
  • human health
  • risk assessment