Platelet procoagulant potential is reduced in platelet concentrates ex vivo but appears restored following transfusion.
Ibrahim Tohidi-EsfahaniShereen TanChuen Wen TanLacey JohnsonDenese C MarksVivien M ChenPublished in: Transfusion (2021)
Storage blunts the procoagulant platelet response to agonist stimulation in PCs. Despite this, conventionally stored PCs have high procoagulant potential following transfusion, with a discordant, persistent reduction in P-selectin response.