New reporter zebrafish line unveils heterogeneity among lymphatic endothelial cells during development.
Maxence FrétaudNam Do KhoaArmel HouelAurélie LunazziPierre BoudinotChristelle LangevinPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2021)
Our Tg(batf3MIN:eGFP) reporter zebrafish line provides a useful system to study LEC populations, of which heterogeneity depends on origin of progenitors, tissue environment and physiological conditions. We further developed a novel fish-adapted tissue clearing method, which allows deep imaging and 3D-visualization of vascular and lymphatic networks in the whole organism.