Synovial Fluid Neutrophils From Patients With Juvenile Idiopathic Arthritis Display a Hyperactivated Phenotype.

Mieke MetzemaekersBert Malengier-DevliesKaren YuSofie VandendriesscheJonas YserbytPatrick MatthysLien De SomerCarine WoutersMieke Gouwy

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2021)

Our data show that neutrophils in inflamed joints of JIA patients have an activated phenotype. This detailed molecular analysis supports the notion that a complex intertwining between these innate immune cells and adaptive immune events drives JIA.

Keyphrases

juvenile idiopathic arthritis
end stage renal disease
immune response
newly diagnosed
ejection fraction
prognostic factors
electronic health record
big data
rheumatoid arthritis
artificial intelligence
machine learning
deep learning