High-Moisture Extrusion of a Dietary Protein Blend Impairs In Vitro Digestion and Delays In Vivo Postprandial Plasma Amino Acid Availability in Humans.

Sam WestAlistair J MonteyneGráinne WhelehanDoaa R AbdelrahmanAndrew J MurtonTim Ja FinniganGiuseppina MandalariCatherine BoothPeter J WildeFrancis B StephensBenjamin T Wall

Published in: The Journal of nutrition (2024)

These data demonstrate that HME delays in vivo plasma amino acid availability following ingestion of a mycoprotein/pea protein blend. This is likely due to impaired gastric phase digestion as a result of HME-induced aggregate formation in the pea protein. This trial was registered at clinicaltrials.gov as NCT05584358.

Keyphrases

amino acid
protein protein
clinical trial
binding protein
study protocol
blood pressure
adipose tissue
metabolic syndrome
oxidative stress
deep learning
artificial intelligence