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Identification of pathogen(s) in infectious diseases using shotgun metagenomic sequencing and conventional culture: a comparative study.

Huan ChenJun LiShanshan YanHui SunChuyi TanMeidong LiuKe LiuHuali ZhangMingxiang ZouXianzhong Xiao
Published in: PeerJ (2021)
Pathogen identification and antibiotic resistance gene prediction by shotgun metagenomic sequencing identification had the potential to diagnose microorganisms in infectious diseases, and it was especially helpful for multiple microbial co-infections and for the cases where standard culture approached failed to identify microorganisms.
Keyphrases
  • infectious diseases
  • bioinformatics analysis
  • single cell
  • candida albicans
  • antibiotic resistance genes
  • microbial community
  • gene expression
  • genome wide
  • dna methylation
  • risk assessment
  • climate change