Prognostic significance of diffuse increased fluorine-18-fluorodeoxyglucose ( 18 F-FDG) uptake within the reticuloendothelial system in lymphoma patients.

F-FDG uptake in lymphoma patients was closely associated with inflammation, whereas diffuse BM uptake was likely attributable to BM infiltration rather than inflammatory changes. Furthermore, both parameters held promise as prognostic indicators for patients with aggressive lymphoma.