HLA matching between donors and recipients improves clinical liver transplant graft survival.
Sarah NabulsiAfolarin A OtunlaJustin SalciccioliDominic C MarshallVincenzo VillaniKumaran ShanmugarajahJoseph ShalhoubPublished in: Liver international : official journal of the International Association for the Study of the Liver (2023)
HLA mismatch significantly reduced graft survival and increased risk of acute rejection. This association was noted only in specific indications. These findings are of potential clinical relevance to organ allocation, allograft matching algorithms, immunosuppression protocols, and transplant surveillance.