Nondiabetic Glucometabolic Status and Progression of Aortic Stiffness: The Whitehall II Study.

Carmel M McEnieryIan B WilkinsonNanna B JohansenDaniel R WitteArchana Singh-ManouxMika KivimakiAdam G TabakEric J BrunnerMartin J Shipley

Published in: Diabetes care (2017)

HbA1c is independently associated with accelerated progression of aortic stiffness in individuals without diabetes. These findings suggest that long-term glucometabolic status, even in individuals without diabetes, could be an important target for preventative strategies against vascular aging.

Keyphrases

type diabetes
cardiovascular disease
aortic valve
glycemic control
left ventricular
pulmonary artery
heart failure
metabolic syndrome
coronary artery
pulmonary hypertension
adipose tissue
skeletal muscle