In vitro nanomaterial testing: unveiling biases through biomolecular corona influence.

This article highlights the recent work of Castagnola, Armirotti, et al. ( Nanoscale Horiz. , 2024, https://doi.org/10.1039/D3NH00510K) on demonstrating that the widespread use of 10% fetal bovine serum in an in vitro assay cannot recapitulate the complexity of in vivo systemic administration.