Candesartan ameliorates brain inflammation associated with Alzheimer's disease.
Nofar TorikaKeren AsrafRon N ApteSigal Fleisher-BerkovichPublished in: CNS neuroscience & therapeutics (2018)
These results thus shed light on the neuroprotective role of candesartan in the early stage of AD, which might relate to modulation of microglial activation states.
Keyphrases
- early stage
- cerebral ischemia
- oxidative stress
- resting state
- white matter
- inflammatory response
- cognitive decline
- lipopolysaccharide induced
- neuropathic pain
- lps induced
- sentinel lymph node
- subarachnoid hemorrhage
- mouse model
- functional connectivity
- blood brain barrier
- brain injury
- squamous cell carcinoma
- spinal cord injury
- radiation therapy
- spinal cord