Efficacy of Retreatment with Oxaliplatin-Based Regimens in Metastatic Colorectal Cancer Patients: The RETROX-CRC Retrospective Study.
Alessio AmatuGianluca MauriFederica TosiKatia BencardinoErica BonazzinaViviana GoriLorenzo RuggieriSabrina ArenaAlberto BardelliSilvia MarsoniSalvatore SienaAndrea Sartore-BianchiPublished in: Cancers (2022)
oxaliplatin retreatment produced further RR in around one-fifth of patients and DCR 57.8%. Efficacy decreased in more pre-treated patients and around one-third of patients discontinued treatment due to adverse events. Translational studies improving patient selection are warranted.